Malignant multiple sclerosis: clinical and demographic prognostic factors
ABSTRACT Patients with malignant multiple sclerosis (MMS) reach a significant level of disability within a short period of time (Expanded Disability Status Scale score of 6 within five years).The clinical profile and 12BM progression of the disease were analyzed in a Brazilian cohort of 293 patients.Twenty-five (8,53%) patients were found to have M